Author:
Kai Knudsen
Updated:
1 August, 2024
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Prasugrel är en hämmare av trombocytaktiveringen och trombocytaggregationen genom att dess aktiva metabolit irreversibelt binder sig till P2Y12-gruppen på trombocyternas adenosindifosfatreceptorer (ADP).
- Det finns ingen känd antidot mot prasugrel
Överväg behandling med:
- Trombocyttransfusion 2-4 enheter.
- Desmopressin (Octostim Injektionsvätska®) 0,3 mikrog/kg SC eller IV; bör begränsas till 2 IV doser (12 -24 timmars mellanrum)
- Tranexaminsyra (Cyklokapron®) 25 mg/kg IV
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